DOI: 10.36347/sjams.2018.v06i06.027

Pages: 2444-2449

This prospective study was conducted in a tertiary level hospital of western Rajasthan, in study duration 48 hospitalised, seropositive patients having CNS manifestation were diagnosed as having co-infection with Cryptococcal meningitis were included in study. There was preponderance of infection in rural, males majority were Labourers, Drivers or Migrant Workers, headache was their main complain. CSF examination by Indian Ink (43 positive), Latex Agglutination for Cryptococcal antigen detection (by Calas) (48) &culture was done on Niger Seed Agar (48) CD-4 Count was done in ICTC BY Fax –Cali bur ( In majority was <50) . In study time there was mortality in 12 patients (25%) patients, out of 9 (75%) died within first week of diagnosis & remaining in second week. So there is significant role of early prompt diagnosis &proper management with antifungal & antiretroviral treatment.