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Scholars Journal of Applied Medical Sciences | Volume-6 | Issue-06
Study of Morphological and Cytogenetic Profile of Patients with Acute Myeloid Leukemia in Kashmir Valley
Nusrat Kounsar, Dr. Sajad Geelani, Dr. Subuh Parvez Khan, Dr. Nusrat Bashir, Dr. Syed Mudasir Qadri, Dr. Javid Rasool, Dr. Fiza Parvez Khan
Published: June 30, 2018 | 138 140
DOI: 10.36347/sjams.2018.v06i06.038
Pages: 2505-2509
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Abstract
Acute myeloid leukemia (AML) is a quickly progressive disease of the myeloid lineage of blood cells. It occurs more commonly in adults than in children, and more commonly in men than women. .While a presumptive diagnosis of AML can be made by examination of the peripheral blood smear when there are circulating leukemic blasts, a definitive diagnosis usually requires an adequate bone marrow aspiration, biopsy and flowcytometry. Cytogenetics study is important in classification of AML and plays an important role in determining the prognosis of the disease. Aim of the study was To study the morphological and cytogenetic profile of AML patients in kashmiri population. This was a retrospective study conducted at Sher-i-Kashmir Institute of Medical Science, Srinagar in the Department of Clinical Hematology on the patients diagnosed as AML patients from January’ 2013 to May’ 2017. The patient data was collected from Regional Cancer Centre. The clinical history, baseline investigations and other specific investigations like bone marrow examination and immunophenotyping was recorded on a preformed proforma. SPSS software was used for statistical analysis.