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Scholars Journal of Applied Medical Sciences | Volume-6 | Issue-06
A Study of Hemodynamic Response to Intubation with Suxamethonium and Org 9426 (Rocuronium)
Narender Bhandari
Published: June 30, 2018 | 144 143
DOI: 10.36347/sjams.2018.v06i06.046
Pages: 2545-2548
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Abstract
There is hemodynamic stress responses to tracheal intubation and can cause adverse cardiovascular events in patients with or without cardiovascular disease. The aim of the present study was to compare the intubating conditions and changes in heart rate and blood pressure achieved after using suxamethonium and rocuronium during intubation in patients undergoing elective surgical procedures. Methods: It is prospective randomized controlled study carried on 90 adult patients with age groups of 20-60 years of either sex. They were posted for elective surgery in Rajiv Gandhi Institute of Medical Sciences [RIMS], Adilabad. They were randomly divided into two groups of (n=45) each. Group I (R) patients received rocuronium at the dose of 0.9mg/Kg and Group II(S) patients received suxamethonium at the doses of 1.5mg/Kg. Results: The heart rates were measured at pre-operative, after the administration of muscle relaxant followed by HR at 0 min, 5 min, and 10 minutes. There was no significant difference in heart rates during all the intervals in both groups. The systolic blood pressure [SBP] preoperative values in Group I was 120.78 ± 11.74 in Group II 117.60 ± 10.12 after the administration of muscle relaxant the values in Group I were 124.82 ± 12.64 and Group II were 132.51 ± 13.77, immediately after intubation the values were group I 130.71 ± 15.37 and Group II were 138.89 ± 11.45 after 5 minutes the values were 117.22 ± 13.29 and 122.64 ± 11.73 in group I and group II respectively and at 10 minutes the values were 112.0 ± 8.86 and 117.5 ± 10.57 all the p values were found to be significant except at the preoperative time. The DBP preoperative in group I was 76.60 ± 8.85 and group II was 74.15 ± 8.81 after the administration of muscle relaxant group I 80.33 ± 11.27 and group II 84.96 ± 10.61 immediately after intubation Group I 86.60 ± 13.21 group II 89.95 ± 9.48. After 5 minutes of intubation Group I 73.96 ± 11.68 and Group II 79.35 ± 9.44 at the end of 10 minutes Group I