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Scholars Journal of Applied Medical Sciences | Volume-6 | Issue-06
Study of Cardiac Autonomic Neuropathy and Its Association with Qtc Dispersion in Type-2 Diabetes Mellitus Patients Attending Rural Medical College
Dr. Mahantesh Ghaniger, Dr. Brijesh K
Published: June 30, 2018 | 130 158
DOI: 10.36347/sjams.2018.v06i06.047
Pages: 2549-2552
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Abstract
The prevalence of diabetes is on the rise, ranked seventh among leading cause of death. One of the major reasons for death among diabetes patient is cardiac autonomic neuropathy. Studies have found that QTc dispersion is an early predictor of cardiac autonomic neuropathy in diabetes, this study was designed to evaluate the association between cardiac autonomic neuropathy with QTc dispersion to improve our knowledge in this area. To evaluate the presence of cardiac autonomic neuropathy in Type 2 diabetes and to co relate autonomic dysfunction. Five standard cardio vascular response tests were carried out (i.e. Valsalva ratio, expiration inspiration ratio, immediate heart rate response to standing, fall in systolic pressure on standing and sustained hand grip test) to determine the severity of cardiac autonomic neuropathy by scoring system. QTc dispersion was determined by subtracting heart rate- corrected minimum QTc interval (QTc min) from maximum QT interval (QTc max) from standard electrocardiogram. Cardiac autonomic neuropathy was studied in 50 diabetic patients and was compared with 50 age and sex matched controls. 17 patients had evidence of cardiacautonomic neuropathy.