DOI: 10.36347/sjams.2018.v06i06.049

Pages: 2558-2562

Acute diarrhoeal disease caused by Vibrio cholerae in many developing nations poses a great public health problem which can kill within hours if left untreated. The present study was undertaken to determine the prevalence of cholera and antimicrobial susceptibility pattern of Vibrio cholerae in a tertiary care hospital at Hyderabad between 2013 and 2017. Design: Retrospective cross-sectional study. Methods: Data of stool samples between 2013 and 2017 from cases of acute diarrhea was analyzed. Stool samples were inoculated onto routine & selective media before and after enrichment. Suspected colonies were identified by standard microbiological techniques and biotyping & serotyping was done. Antimicrobial susceptibility testing was done by Kirby Bauer disk diffusion technique. Stool culture data and susceptibility pattern were analyzed and presented. Results: A total of 133 isolates of Vibrio cholerae were obtained from 6441 stool samples (2.06%), of which 34 (2.73%) were obtained in 2013, 33(2.68%) in 2014, 17(1.13%) in 2015, 47(3.02%) in 2016 and 2(0.21%) in 2017. Maximum isolation was seen between April and August with a peak incidence in July. Out of 133 isolates, 112 (84.2%) isolates were from adults and there was female (52.6%) preponderance. All isolates were Vibrio cholerae O1 El Tor of which Ogawa comprised 116(87.2%), Inaba 17(12.8%) and Hikojima nil.