DOI: 10.36347/sjams.2018.v06i06.055

Pages: 2596-2604

The aim of this study was to determine the correction factor for the calculation of 24 hour I-131 thyroid uptake using a Gamma Camera with HEGP Collimator in patients with thyroid disease. This study we initially performed on phantom and in second phase it was performed on randomly chosen 25 patients to ascertain the appropriate value of correction factor for the calculation of gamma camera based thyroid uptake. In these patients had benign thyroid disorders and most of who had been referred for Thyroid evaluation before radioiodine-131 treatment. For this study Neck Phantom (Capintec Inc., Ramsey, USA), made up of Lucite, Gamma Camera (Discovery NMCT/670, GE make, USA), Thyroid uptake probe (Captus 3000, Capintec Inc, USA), Pipettes (Tarson made) and Dose Calibrator (Captus 3000, Capintec Inc, USA) were used and fine tune the others relevant parameter. The desired amount of radioiodine-131 Sodium Iodide solution activity i.e. 1.85MBq (50 μCi) was prepared with the help of pipetting technique and was administered to the patient with adequate flushing of the vial to ensure maximum oral administration of the dose. Radioiodine-131 uptake was usually measured at 25 cm distance from the face of the crystal to the anterior neck or phantom and also 24 hours thyroid uptake was calculated by using a probe-based method and a camera-based method with a high-energy parallel-hole (HEGP) collimator.