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Scholars Journal of Applied Medical Sciences | Volume-8 | Issue-03
Immune Thrombocytopenic Purpura in Children - A Review
Ponnumony John Solomon, Alen Chidambaram Priya Margaret
Published: March 30, 2020 | 63 42
DOI: 10.36347/sjams.2020.v08i03.050
Pages: 1062-1066
Immune Thrombocytopenic Purpura is one of the most common bleeding disorders of childhood. It presents with petechiae and bruising in a well looking child. It is caused by immune mediated destruction of platelets. Nowadays many centres in the world do not do bone marrow examination for diagnosis in typical cases of immune thrombocytopenic purpura. Majority of them get cured within 12 months, but about 20% of the cases continue to bruise/bleed on and off beyond 1year also. Most children with ITP do not need treatment, but sometimes there will be need to treat because of the risk of life threatening bleeding. Steroids, IVIg, and Anti-D (Rho) immunoglobulin are standard first line treatments depending upon the situation. When the platelet count is very low there is a risk of intracranial bleed, and hence appropriate treatment should be given in such cases. The terminology and treatment protocols have changed since the time of its first report. Hence it is better to go for a review in this topic.