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Scholars Journal of Applied Medical Sciences | Volume-6 | Issue-07
Efficacy of Sevoflurane on Intubating Conditions In General Anesthesia under Rocuronium-A Comparative Study
Dr. Pratibha Kumari, Dr. Ramu Valluri, Dr. Priyanka Gotluru
Published: July 30, 2018 | 133 130
DOI: 10.36347/sjams.2018.v06i07.044
Pages: 2858-2862
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Abstract
The ease with which endotracheal intubation is performed depends upon degree of muscle relaxation, depth of anaesthesia and skill of anaesthesiologist. This is prospective, randomised; double-blind study conducted at Kamineni Academy of Medical Sciences and Research Centre, Hyderabad.The aim of this study is to compare the effect of sevoflurane on intubation time and intubating conditions when used along with rocuronium. A 70 patients aged between 30 to 50 year of both genders, weighting from 40 to 70kg coming for elective surgeries under general anaesthesia included. They are divided in two groups, Group R received 0.8 mg/kg rocuronium, and Group RS received 0.8 mg/kg of rocuronium with 2% sevoflurane. Intubating conditions were assessed by cooper scoring system. In Group R, 18patients showed excellent, 14 patients good and 3 patients poor intubation conditions and in group RS 21patients showed excellent, 6 patients good and 1 patient poor intubation conditions respectively. The time for loss of thumb adduction was 99.81±9.3 in Group R compared with 62.03±5.2s in Group RS and The onset time of intubation was 100.65±8.6s in Group R compared with 58.62±6.5 in Group RS. These timings were significantly reduced in the Group RS compared to Group R. Rocuronium 0.8 mg/kg produces good intubation conditions at 100 sec when compared with Rocuronium 0.8 mg/kg along with 2% sevoflurane provides excellent intubating conditions within 60–66 s without any adverse effects in elective surgeries in patients with stable haemodynamics.