DOI: 10.36347/sjams.2018.v06i08.028

Pages: 3085-3089

Urolithiasis disease is a function of a number of risk factors. Present objective is to study the urinary risk factors in urolithiasis patients from Purnia division of Bihar (India). The study would lead to an understanding of the various metabolic abnormalities leading to urinary stone formation in this region. Twenty four hour urinary calcium, magnesium, oxalate, phosphate, uric acid and citrate were estimated in 100 urolithiasis patients (66 males & 34 females) in the age group of 18-55 yrs. Fifty normal healthy persons (30 males & 20 females) in the age group of 20-55 yrs, who served as controls, were also studied for the above urinary parameters. Results revealed that hypercalciuria, hyperoxaluria and hypocitraturia are the main risk factors of urolithiasis in the region. Hyperuricosuria, hypophosphaturia and hypomagnesuria also showed up as marginal risk factors in the urinary stone patients. As such, urolithiasis patient from Purnia division of Bihar should invariably be tested for urinary calcium, oxalate and citrate levels. Urinary uric acid, phosphate and magnesium levels may also be assessed additionally. The treatment / prophylaxis strategy should be to correct these metabolic abnormalities so that the recurrency of the stone episode could be checked.