DOI: 10.36347/sjams.2018.v06i08.047

Pages: 3176-3181

The aspiration of peritoneal fluid is a bedside procedure. The routine, microscopic and cytological examinations of peritoneal fluid have been an important diagnostic value to find out the cause of ascites. The routine examination can help in differentiation of transudative and exudative fluid, microscopic examination, culture sensitivity and PCR testing can help to identify microbiological organism and cytological examination helps in the diagnosis and typing of malignancy in peritoneal fluid. The present study includes 110 cases of ascites. The aspiration of peritoneal fluid was done with aseptic precautions and fluid was submitted for routine and microscopy, cytological examination and ADA estimation. The transudate type of fluid detected in 46(41.8%) cases and exudative fluid detected in 64(58.2%) cases. The inflammatory fluid in 37(57.8%) cases and malignancy in 29(57%) case were detected and 8(12.5%) cases were suspicious of malignancy. Adenocarcinoma in male and carcinoma of ovary in female is commonest causes of malignancy. In case of malignant peritoneal fluid different cytomorphological features along with clinical and radiological findings help to locate the primary tumor in abdomen. The type of malignant lesion can be confirmed by histopathology after surgery or by various available biopsy techniques like laparoscopic and endoscopic biopsy. ADA level in body fluids is 93.5% specific and 95.9% sensitive for diagnosis of tuberculous peritoneal fluid and positive predictive value was 95.9% and negative predictive value was 92.1%. ADA level] than 40 IU/ML is diagnostic of tuberculous etiology of peritoneal fluid.