DOI: 10.36347/sjams.2018.v06i08.048

Pages: 3182-3188

To find out the various clinicopathological presentations of gall stone disease with special relation to H,pylori infections of Gall Bladder. Institution based prospective observational study in a tertiary care centre. Study was conducted on patients who attended the department of General Surgery of Medical College Kolkata. A total of 50 patients were taken up for the study. Rapid urease test of the gall bladder mucosa was positive in 5 out of 10 male patients (50%) who were admitted with chronic calculus cholecystitis. Rapid urease test was positive in 17 out of 40 female patients (42.5%) who were admitted with chronic calculus cholecystitis. So total 22 patients out of 50 (44%) were affected with H. Pylori infections. IgG antibody kit test were positive in 3 out of 10 male patients (30%) who were admitted with chronic calculus cholecystitis. IgG kit test were positive in 7 out of 40 female patients (17.5%). Total 10 out of 50 patients (20%) with chronic calculus cholecystitis were IgG positive i.e. chronic H.Pylori infections. The identification of H Pylori antibody IgG in serum and H Pylori infection in gallbladder and pathological changes in gallbladder among the patients with gallstones provides a strong evidence of association of the organism with chronic calculus cholecystitis or gallstone diseases and H Pylori may be an etiological agent in gallstone formation. Further studies required to determine its role in gall bladder cancer formation