DOI: 10.21276/sasjm.2019.5.4.1

Pages: 69-71

Conjunctival amyloidosis is a very rare condition, mostly occurring as a local deposition of amyloid and very rarely in association with systemic involvement. Our purpose is to present a rare case of bilateral conjunctival amyloidosis with systemic involvement. A 58-year-old gentleman presented with bilateral eyelid ecchymosis and chemosis for past 2 years. Ocular examination found in both eyes a yellow-pink diffuse mass extending from the inferior bulbar conjunctiva to the lower fornix. Examination of the fundus revealed a single retinal cotton-wool spot. CT scan showed hypertrophy and infiltration of the orbital fat. Biopsies of conjunctival mucosa, bone marrow, perirenal fat, stomach, duodenal, and colic mucosa showed amyloid deposits. Immunofixation of blood samples revealed monoclonal gammopathy. Thus, patients with conjunctival amyloidosis should be examined comprehensively and regularly for systemic amyloidosis because of its poor life prognosis.