DOI: 10.36347/sjams.2018.v06i09.024

Pages: 3357-3360

Pre-eclampsia is a condition of high blood pressure during pregnancy and it is one of the important cause of maternal or fetal morbidity and mortality. Recently the pieces of evidence have found that increases in homocysteine levels are associated with adverse outcomes. In the present study, we tried to evaluate the serum Homocysteine, Serum Folate, and Vitamin B12 levels in pre-eclamptic pregnant women and eclamptic pregnant women compared with normal pregnant women. Methods: This cross-sectional prospective study was done in the Department of OBGY and Biochemistry, Prathima Institute of Medical Sciences, Naganoor, Karimnagar study period 9/8/2017 to 9/7/2018. Fifty females of normal pregnancy, thirty-five patients of pre-eclampsia and twenty-eight patients of eclampsia were included in the study. Pre-eclampsia was diagnosed when the BP was higher than 140/90mmHg observed on at least 2 occasions after the 20th week of pregnancy and protein urea of > 300 mg/24 hours. Eclampsia was defined as the onset of convulsions or coma in the patients who has signs and symptoms of pre-eclampsia.