DOI: 10.36347/sjams.2018.v06i09.066

Pages: 3568-3571

Hormones are one of the principal factors in intercellular and inter-organ communication. The thyroid hormones are crucial for normal functioning because of their control over body’s basal metabolic rate, as well as growth, development, and differentiation of many cells/organs in the body.The present study was based on a cross-sectional study design carried out at the outpatient department of Maheshwara Medical College & Hospital from January 2017 to July 2018. Serum levels of free thyroxin (FT4), thyroid stimulating hormone (TSH), free testosterone, prolactin (PRL), follicle-stimulating hormone (FSH), and luteinizing hormone (LH) were measured using immunoassay commercial kits in both groups. The normal reference ranges for thyroid hormones were as follows: TSH, 0.3 to 5.0 IU/mL and T4, 4.5 to 12.5 g/dL. Erectile dysfunction was evaluated using International Index of Erectile Function (IIEF-5) questionnaire. The results were averaged as (mean ± standard deviation) for each parameter subgroups separately. Each variable, including age, serum levels of hormones, sperm parameters, and IIEF-5 scores, were assessed by sample t test.In our present study, age of hypothyroid subject group and normal control group is found to be non-significantly related (P = .367). Similarly, no significant relation was also noted among the FSH levels (P = .834) of the two groups. There was significant (P < .001) relation among the hypothyroid and normal groups in IIEF-5 scores, Serum PRL level, sperm count, sperm motility and morphology. Abnormal thyroid function resulted in decreased male fertility and/or impaired sexual activity. In hypothyroid subjects, high levels of PRL may affect sexual drive and result in occurance of Erectile Dysfuction. Thyroxin administration can improve fertility and reverses the effects of hormonal abnormalities. These observations show that sexual dysfunctions are almost always multifactorial (physical and psychological factors). In the present study, patients