DOI: 10.36347/sjams.2018.v06i09.068

Pages: 3575-3578

Dengue fever (DF) is the most common acute febrile viral disease among all the arthropod-borne viral diseases caused by a single-stranded RNA virus of Flaviviridae family. The present study was undertaken to evaluate the hematological profile of seropositive (IgM) dengue fever patients and co-relate the hematological data to predict the severity of the disease. The study was conducted in Fatima Institute of Medical Sciences, Kadapa, and Andhra Pradesh. Total 140 IgM dengue positive cases were evaluated to know the haematological changes. The dengue positive cases were classified based on the clinical history, signs and symptoms, Haematological findings of the study with reference to the WHO criteria for dengue case definition. Demographic profile of the study population reveals that not much difference in male and female ratio (1.2:1). The most important abnormal haematological findings were platelet counts less than 50,000/cumm (38.5%). Haemoconcentration was also observed in 15% in results to the plasma leakage. Conclusion: Estimation of hematological findings during the critical phase (24-48 hrs) among DHF patients is crucial for the early detection of plasma leakage and to determine the adequacy of fluid therapy.