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SAS Journal of Medicine | Volume-9 | Issue-10
Hyperthyroidism and Pregnancy
Sara Ijdda, S. Rafi, G.H. Elmghari, N. El Ansari
Published: Oct. 3, 2023 | 101 95
DOI: 10.36347/sasjm.2023.v09i10.001
Pages: 1043-1051
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Abstract
Introduction: Hyperthyroidism in pregnancy is defined by low TSH, below the specific reference values of each trimester with high levels of free T3, free T4 or both. Source of serious complications for both the mother and the fetus. The aim of our study is to determine the clinical, paraclinical, etiological and therapeutic aspects. Material and Methods: We have collected in this work the cases of hyperthyroidism duringpregnancy encountered in the endocrinology, maternal intensive care and gynecology departments of the Marrakech University Hospital. Results: we have collected 32 cases of hyperthyroidism during pregnancy. The average age was 29 years old. Functional signs were dominated by uncontrollable vomiting and weight loss. As for the thyroid assessment, the average TSH level was 0.017 with an average T4 level of 53.30 and T3 of 15.74. The etiologies were dominated by transient gestational hyperthyroidism (TGH) and Graves' disease. The management was essentially based on hydro-electrolyte rebalancing, then the etiological treatment in a second step. Discussion: Hyperthyroidism is considered to be the second endocrinopathy in pregnant women, after gestational diabetes. It would be present in 1 to 3% of pregnant women, the most common causes are Graves' disease and TGH. Conclusion: Pregnancy hyperthyroidism is a frequently encountered situation. The identification of the cause of hyperthyroidism must be established because it guides the follow-up andpregnancy care.