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Scholars Journal of Medical Case Reports | Volume-11 | Issue-10
Fortuitous Discovery of Primary Hodgkin's Lymphoma of the Thyroid in a Total Thyroidectomy Specimen: Case Report
Papys Mendes, Mouhoubo Ibrahim Houssein, Zakia Bernoussi
Published: Oct. 29, 2023 | 71 55
DOI: 10.36347/sjmcr.2023.v11i10.043
Pages: 1891-1894
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Abstract
Primary thyroid lymphomas are a rare clinical entity, which do not exceed 5% of diagnosed lymphomas, occur more frequently in women than in men. The relationship with chronic thyroiditis is well known. The Hodgkin subtype, even rarer, characterized by the presence of mononuclear Hodgkin cells and multinuclear Reed-Sternberg cells observed in a cellular background rich in lymphocytes, histiocytes, plasma cells and/or eosinophils or neutrophils little described in the literature. The diagnostic confirmation is most often carried on the surgical specimen. We will report a case of a 22-year-old patient, with no particular pathological history, who presents with an increase in volume in the anterior part of the neck, the clinical diagnosis mentioned was multi-nodular goiter, including the gesture of total thyroidectomy Have been realised. After histological analysis of the specimen, the pathologist evokes normal and macrovesicular hyperplasia, with the presence of a process of lymphomatous morphological criteria in the right lobe, requiring an immunohistochic study. After confirmation of Hodgkin's lymphoma by immunohistochemistry, the patient underwent chemotherapy under the ABVD protocol (adriamycin, bleomycin, vinblastine and dacarbazine) and radiotherapy.