DOI: 10.36347/sjmcr.2023.v11i10.049

Pages: 1913-1916

Introduction: Hypothalamic hamartomas (HH) are rare tumor malformations that can manifest as complex partial seizures refractory to anticonvulsants in adulthood and behavioral disturbances. The pathology can be misdiagnosed due to its rarity. Objectives: We attempt, from a clinical case, to alert neurologists and psychiatrists to the neurological and psychiatric symptoms of HH, knowing that they may encounter a very small number of these cases in their practice. Methods: We report the case of a 45-year-old man complaining of seizures manifested by falls, tonic spasms of the limbs and hypermotor activities. Her seizures began at the age of fifteen and presented as a deviated eye, followed by frequent seizures of varying frequency. The patient also had symptoms of intellectual disability. He was hospitalized in our psychiatry department for the management of a suicide attempt made in a hallucinatory setting, comorbid with drug-resistant epilepsy. Results: Neuroimaging concluded with the diagnosis of HH. The patient became a candidate for surgery after that. In our clinical case, the patient was able to benefit from a radio surgical treatment Gamma Knife (GK). Conclusion: In this case, the underlying etiology of the seizures and psychiatric manifestations was diagnosed thirty years after the onset of symptoms. Therefore, neurologists and psychiatrists should consider it in patients with suspicious signs and symptoms.