DOI: 10.36347/sjmcr.2023.v11i11.013

Pages: 1969-1974

Post-covid19 necrotising vasculitis is a recently introduced pathological entity, representing one of the rare extra-respiratory covid 19 infections that can threaten vital and functional prognosis. Our series included 5 children, three girls and two boys. The average age of our patients was 6 years. The median time between exposure to the SARS Cov2 virus and the onset of clinical symptoms was 4.5 weeks. The clinical expression of post-covid vasculitis was polymorphic, including mainly skin lesions with cyanosis in 60% and necrotic purpura in 40% of cases. Cardiac anomalies were noted in only one patient presenting myocarditis with pulmonary arterial hypertension. No renal or ocular anomalies were observed in any of our patients. The PCR COVID 19 was positive in only one patient, associated to positive SARS Cov2 IgM and IgG serology. The other four patients had only positive IgG serology. The diagnosis of necrotising vasculitis was confirmed by histological study of skin biopsies. On the basis of all the clinical, biological, radiological and histological criteria, the diagnosis of acute necrotising vasculitis post SARS COV 2 infection was set, since all the biologic tests were normal apart from the recent coronavirus infection. Our patients received medical treatment including oral corticosteroids and anticoagulants, with a good clinical and biological outcome, except for two children who underwent amputation of both legs.