DOI: 10.36347/sjams.2023.v11i11.017

Pages: 1958-1963

Introduction: Intense kidney harm (AKI) taking after cardiac surgery is one of the common complications and expanding its frequency. AKI is considered as an independent risk factor for morbidity and mortality in hospitalized patients, especially in intensive care unit and in patients undergone major surgery like cardiac surgery. This think about assesses the impact of preoperative expanded serum uric acid (SUA) levels in comparison with other known hazard variables on the pathway of AKI after cardiac surgery. Acute kidney injury after cardiac surgery portends significant morbidity and mortality. Aim of the Study: The aim of the study was to investigate the determinant factors of acute kidney injury (AKI) after isolated off pump coronary artery bypass grafting (CABG). Methods: This was a prospective, cross-section, observational study conducted in the Department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh from July 2021 to June 2022. During 1 year, 140 patients experienced elective coronary artery bypass surgery. Result: A total of 140 patients group A with uric acid < 5.5 mg/dl (n=70) was 52.82 ± 5.71 years old & group B with uric acid > 5.5 mg/dl (n=70) was 53.56 ± 5.34 years (p = 0.430). We found the BMI Mean ± SD was 28.57 ± 2.29 in the group A versus 29.20 ± 3.31 in the group B (p = 0.193). In our study group A uric acid < 5.5 mg/dl, 10 (14.29%) patients had AKI versus 45 (64.29%) in group B uric acid >5.5 mg/dl. And 60 (85.71%) patients had no AKI in group A versus 25 (35.71%) in group B (p = <0.001). Conclusion: Elevated preoperative serum uric acid level was associated with higher incidence of AKI, longer mechanical ventilation time, ICU stay, hospital stay and overall postoperative complications following OPCAB surgery.