DOI: 10.36347/sajb.2018.v06i04.008

Pages: 348-352

Ovarian cancer is a disease whose etiology is thought to be due to incessant ovulation and hormonal imbalance and is the most common cancer in women with a lifetime risk of 1 in 100 women. Among various types of ovarian malignancy, epithelial ovarian cancer is reported to be the most common histological type. The objective of the study is to estimate serum vitamin D levels and evaluate association of vitamin D levels with the risk of epithelial ovarian cancer. This prospective case control study was done over a period of 2 years (October 2015 to October 2017) in a tertiary care private teaching hospital. Hundred women were included in our study, of which fifty were epithelial ovarian cancer women with the age group between 20 to 80 years and fifty healthy women as control. 2ml blood sample was drawn in plain vacutainer to measure the serum vitamin D levels and were estimated by Electro-Chemi Luminescence Immuno Assay (ECLIA). Serum vitamin D levels were significantly lower in ovarian cancer women compared to controls (p <0.001). We conclude that Vitamin D level can be a biomarker which was found to be significantly lower in ovarian cancer group.