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Scholars Academic Journal of Biosciences | Volume-6 | Issue-04
Pre-Operative Evaluation of Ovarian Tumours by Risk of Malignancy Index 2 at a Tertiary Care Centre of Rajasthan
Dr. Lata Rajoria, Dr. Sunita Singhal, Dr. Premlata Mital, Dr. Richa Ainani, Dr. Alka Batter, Dr. Monika Agarwal, Dr. Kavita Chaudhary, Dr. Urmila, Dr. Aditi Gupta
Published: April 30, 2018 | 128 131
DOI: 10.36347/sajb.2018.v06i04.009
Pages: 353-356
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Abstract
A pelvic mass is one of the most frequent indication for referral to a higher centre. The accurate diagnosis of an adnexal mass is a challenge for the gynaecologists. RMI 2 is a multiparametric index developed to discriminate benign and malignant tumours. The purpose of the study was to evaluate the ability of RMI 2 to discriminate between benign and malignant ovarian tumours at a tertiary care centre of Jaipur. This was a prospective observational study.180 patients with ovarian tumours admitted for laparotomy was included in the study after obtaining written informed consent. Menopausal status, USG score and Serum levels of CA 125 measured for all and RMI 2 was calculated. Diagnostic ability of RMI was evaluated. On univariate analysis, there was significant difference in patients with benign and malignant tumour on the basis of menopausal status, USG score & CA 125 levels. At a cut off of 200, RMI 2 had a sensitivity of 80% (63.06 - 91.56), Specificity of 97.24 (93.09 - 99.24), positive predictive value of 87.50%, negative predictive value of 95.27% and diagnostic accuracy of 93.89%. RMI 2 is a simple mathematical formula used to discriminate benign and malignant ovarian tumours. It will help in selective referral of patients to higher centres.