DOI: 10.36347/sajb.2018.v06i05.005

Pages: 416-420

Cryoprecipitate is a product rich is clotting factors and is obtained from freezing and thawing of the plasma. It is originally developed as a therapy mainly for patients with anti-hemophilic factor deficiency, or hemophilia A which is a genetic disorder, cryoprecipitate has been in use for more than 60 years. However, cryoprecipitate is no longer administered according to its original purpose, and is now the usage has been shifted to replenish fibrinogen levels in patients with acquired coagulopathy, such as in clinical settings with hemorrhage including cardiac surgery, trauma, liver transplantation (LT), or obstetric hemorrhage. The main aim of this study was to know about the usage of cryoprecipitate in our institute. This is a retrospective record based audit carried out from January 2017 to March 2018. The requisition forms and the patients who received cryoprecipitate during this time were reviewed by using their medical records (including recipient age, sex, clinical diagnosis, and related management) and clinical laboratory. The number of concentrates of cryoprecipitate used and the number of transfusions (pools of concentrates) used were noted. Each requisition form was evaluated and the indication mentioned in the request form was labeled as appropriate or inappropriate. When the clinical condition matched with the absolute indications of cryoprecipitate usage then the usage was labeled as appropriate. Total 746 cryoprecipitate issues were done. 69.5 % were Females and 30.5 % Males. Most of the cases were in the age group 41years to 55 years. Most of the cryoprecipitate units were utilized by medical oncology department and least units were used by plastic surgery, rheumatology, surgical oncology, cardiology and emergency medicine. Most common clinical diagnosis for which most of the cryoprecipitate units were used was multiple myeloma and least units were used for mitral valve replacement surgery. In this study, the majority of the utilization was appro