DOI: 10.36347/sjams.2020.v08i05.030

Pages: 1314-1322

Background: The incidence of dengue has grown dramatically across the world in the recent decade. According to World Health Organisation (WHO), about 50-100million new dengue infections are estimated to occur annually in more than 100 endemic countries, with a steady increase in the number of countries reporting the disease. This study describes clinical and immunological profile of dengue fever in patients admitted to the hospitals attached to Bangalore Medical College and Research Institute, Bangalore. Materials and methods: This is a retrospective study including 200 patients of dengue fever from November 2017 to April 2018. Results: Amongst 200 patients, who presented with dengue fever, 58.5% were males and 41.5% were females. About 37% were in the age group of 21 to 30 years with mean age of study group being 33.7 ± 12.1 years. All of them (100%) had fever at the time of presentation followed by generalised bodyache(). 13.5% of them had hypotension. They were treated accordingly. This study showed NS1 positivity had significant association between platelet transfusion, bleeding manifestations and raised ALT levels. Our study showed mortality rate of 3% for dengue fever. Conclusions: Early diagnosis and timely intervention are needed to prevent life threatening complications.