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Ghana Alternative Medicine Journal | Volume-4 | Issue-04
A Study of Clinical Spectrum, Laboratory Profile and Outcome of Dengue Fever in Children
Dr. Md. Jashim Uddin, Dr. Mohammed Razzak Mia, Dr. A.N.M. Mizanur Rahman, Dr. Mohammad Bhuiyan Abdus Samad Azad, Dr. Md Amir Ul Mulk, Dr. Nilufar Yeasmin
Published: Nov. 29, 2023 | 460 211
DOI: 10.36347/gamj.2023.v04i04.005
Pages: 150-155
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Abstract
Background: Dengue is one of the dreaded fevers of paediatric age group with variable presentations and complications. Understanding the knowledge of presentations and associated features would help to predict the severity of the disease. Dengue fever presents as a common fever with dangerous complications. Infection with dengue virus (DENV) provides lifelong immunity to the serotype affected providing partial and transient protection against re infection with the other three serotypes. Objective: To evaluate the clinical and laboratory features, as well as the consequences of dengue fever in children. Materials and Methods: This was an observational, cross-sectional study done by the Department of Paediatrics at Narsingdi's 100-bed district hospital from July 2021 to June 2022. A total of 100 dengue fever cases were enrolled and categorised according to WHO guidelines. All children under the age of 18 were screened and validated using the NS1 antigen and the Ig M and Ig G fast antibody detection serological tests. The study included all of the positive dengue patients. Malaria, typhoid, chikungunya, and other causes were excluded from the study. A systematic questionnaire was used to collect the clinical and demographic profiles. Haematological values were recorded and monitored till the patient was discharged. Results: The differences in fever, myalgia, vomiting, stomach discomfort, petechiae, bleeding symptoms, retro orbital pain, and hepatomegaly between the two groups were not statistically significant (p>0.05). Total leukocyte count (cells/mm3), SGPT (IU/L), SGOT (IU/L), Platelet count (/mm3), Haematocrit (%), Dengue serology, Hepatomegaly, Splenomegaly, Gall bladder wall thickening, and ascites were all important screening techniques for severe dengue fever diagnosis. This was statistically significant (p 0.05) when comparing severe dengue fever groups to non-severe dengue fever groups. Conclusion: Among the more common clinical characteristics were ........