DOI: 10.36347/sajb.2016.v04i05.013

Pages: 429-431

Rheumatoid arthritis (RA) is a chronic disease with unknown etiology. The aim of this study to estimate the serum Vit. E, Malondialdehyde (MDA) and Reduced glutathione (GSH) in RA patient and comparison with normal healthy subjects. In the study the serum level of vit. E was estimated by method given by Catignani & Bieri. Serum MDA is estimated by a thiobiteric acid assay method and serum GSH were determined by the method of Paglia and Valentine. Serum level of Vit.E and Reduced glutathione were significantly reduced in RA patient as compared to control group (p <0.005 for Vit.E and p< 0.005 for GSH). Serum MDA level in RA patient was significantly higher than control group.