DOI: 10.36347/sjams.2020.v08i05.038

Pages: 1365-1369

This work was aimed at testing the effectiveness of a locally sourced and fortified lipid solvent, on influenza A Disease virus in some infected poultry birds at the National Veterinary Research Institute, Vom (NVRI) Plateau State of Nigeria. The research was designed by randomly blocking (during lipid dilution process) thirty-five Guinea Fowls (35) in groups of seven (7) based on lipid dilutions viz; six (6) lipid dilution groups and the control group. Dilutions from 10-5 to 10-10 were used for the assay. 0.1ml of the respective dilutions was transferred to sterile Bijou bottles labelled with the corresponding lipid solvent dilution. Thereafter, equal volumes of 4HA unit concentration of neat suspension of influenza virus strain (A/PR/6/32) was added to each bottle for other critical stages of the neutralization/haemagglutination inhibition assays. It was observed that none of the Guinea fowls treated with equal mixture of the fortified lipid solvent and the influenza virus strain came down with the disease. While most of those treated with the influenza virus strain were significantly infected (P<0.05).