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Scholars Journal of Applied Medical Sciences | Volume-11 | Issue-12
Comparison of Trans-Resveratrol (98% Pure) with Resveratrol (40%) as Rejuvenation Therapy on Ovarian Reserve Parameters and Pregnancy Outcomes in Infertile Adult Women with Poor Ovarian Reserve, Undergoing Assisted Conception Cycles – A Double Arm, Randomized, Open Label Study
Dr. P. M. Gopinath, Dr. Sahityalakshmi Manoharan
Published: Dec. 16, 2023 | 85 71
DOI: 10.36347/sjams.2023.v11i12.010
Pages: 2049-2052
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Abstract
This is a Phase IV Randomized, double arm Open labelled trial, conducted at SIMS hospital, Vadapalani, Chennai. It involves all women seeking fertility treatment with poor ovarian reserve, who are planned to undergo assisted conception cycles, including IUI & IVF. The study included women aged between 21 and 45 years, with Poor ovarian reserve with regular menstrual cycles (21–35 days), prestimulation parameters (AFC<5, AMH<1.2 ng/ml), History of previous poor ovarian response </= 5 oocytes with a conventional stimulation protocol, Couples undergoing the ICSI cycle with ejaculated sperm. The data collected was subjected to statistical testing. The groups were compared in terms of their demographic features and both the groups was found to be equally distributed. Trans-Resveratrol shows that this drug has no advantage over Resveratrol, therapeutically or statistically advantage.