DOI: 10.36347/sjds.2019.v06i01.001

Pages: 1-3

Introduction: Periodontal disease is a multifactorial disease characterized by chronic inflammatory process that is caused by interaction between virulent microorganisms and host responses, resulting in connective tissue destruction that supports bone. Aim: The present study was aimed to assess serum LDH levels in patients of chronic periodontitis and age and sex matched healthy controls. Materials & Method: The present study was conducted in the department of Biochemistry in collaboration with the Department of Periodontics, PGIMS, Rohtak. A total of 60 subjects were enrolled in the study, which were divided into two groups. Group I was the case group which included 30 newly diagnosed patients of chronic periodontitis and group II was the control group which included 30 age & sex matched subjects. LDH levels were analyzed by autoanalyser on the same day in both cases and controls. Results: In the present study mean serum LDH levels were found to be higher in chronic periodontitis patients as compared to their age and sex matched healthy controls. (426.12 + 109.25 U/L and 141.8+49.11 U/L respectively). This difference was found to be statistically highly significant (p=0.000). Conclusion: Based on the results of our study it was concluded that serum LDH levels were increased in chronic periodontitis. Therefor serum LDH can be considered as feasible and useful biochemical marker in diagnosis of chronic periodontitis