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Scholars Journal of Medical Case Reports | Volume-12 | Issue-01
Primary Biliary Cholangitis in Men: A Rare and Particular Presentation (About 2 Cases and Review of the Literature)
Chama El Manjra, Abderrahmane Jallouli, Ibtissam Bounouar, Oussama Nacir, Fatima Ezzahra Lairani, Adil Ait Errami, Sofia Oubaha, Zouhour Samlani, Khadija Krati
Published: Jan. 16, 2024 | 58 31
DOI: 10.36347/sjmcr.2024.v12i01.017
Pages: 67-70
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Abstract
Primary biliary cholangitis (PBC) is a rare etiology of cholestatic jaundice in men. We report two rare cases of PBC in men revealed by chronic cholestasis (jaundice, pruritus, dark urine, discolored stools, ALP greater than 1.5 times the upper limit and GGT greater than 3 times the upper limit). The first case had positive anti-mitochondria type 2 antibodies, while in the second case they were negative with positive anti gp-210 antibodies. The histological study of liver biopsies in the first case confirmed PBC. The second case was diagnosed at the stage of cirrhosis.