DOI: 10.36347/sjams.2020.v08i07.012

Pages: 1701-1705

Back ground: Biliary tract cancers refer to as group of cancers that arise from epithelial lining of the gall bladder and bile ducts peri-hilar and extra hepatic biliary tree and peri-ampullary tumors. Though biliary tract cancer is a rare entity. Objective: In this study our main goal is to evaluate the sociodemographic status of biliary tract carcinoma patients. Method: This cross-sectional study was conducted in Department of Oncology Bangabandhu Sheikh Mujib Medical University, Dhaka Medical College and National Institute of Cancer Research and Hospital, Dhaka from January 2018 to June 2019. 78patients with advanced biliary tract carcinoma (Stage IV), attending the out-Patient department were selected as sample where 39 patients received - Oral Capecitabine plus injectable Cisplatin (Arm-A) and 39 patients received injection Gemcitabine plus Cisplatin (Arm-B). Purposive sampling was done and data were analyzed by SSPS 21. Results: In this study, the majority of the patients were in the 50 to 59 years age groups in both the arms, range from 37 -70 years. Most of the patients were in the group 2 in both the arms. It was 51.29% and 56.41% in arm A & B respectively. 53.85% and 43.59% patients from Arm A and B had the primary tumor in the Gall Bladder respectively. 35.89% and 43.58% patients from Arm A and B respectively had the primary tumor in the Cholangiocarcinoma (CCA). On the other hand, 10.26% and 12.83% patients from Arm A and B had the primary tumor in the Periampullary Carcinoma respectively. Most of the patients (66.66% in Arm A and 66.66% in Arm B) had liver metastasis. Conclusion: In conclusion we can say that, this study demonstrated that, biliary tract cancers are a highly aggressive human malignancy that is difficult to diagnose. Most of the cases site of metastasis increase gradually which compare from similar studies in the literature.