DOI: 10.36347/sjmcr.2024.v12i03.007

Pages: 261-266

Osteoblastoma (OB) is a rare benign osteogenic tumor, primarily found in the axial skeleton and long tubular bones. It accounts for <1% of all primary bone tumors, mainly affecting young adults. Maxillofacial involvement is rare, often manifesting in the mandible. Osteoblastoma's pathogenesis is unclear, with slow growth and varied clinical presentations. Radiologically, it appears as a well-defined, osteolytic lesion with sclerotic rims. The definitive diagnosis relies on histopathology, with immunohistochemistry aiding in challenging cases. Differential diagnoses include fibrous dysplasia, osteoid osteoma, osteomas, cemento-ossifying fibroma, and low-grade osteosarcoma. Surgical excision with safety margins is the standard treatment, while radiotherapy may be considered for certain cases. Prognosis is generally good, but long-term follow-up is essential due to recurrence risks, particularly in aggressive forms. Malignant transformation can occur, emphasizing the importance of careful diagnosis and management.