DOI: 10.36347/sjams.2020.v08i08.004

Pages: 1818-1822

Background: Corneal collagen cross-linking (CXL) is a promising method in the treatment of keratoconus (KCN); however, long-term results of this treatment modality are under-represented in the literature. Objective: In this study our main goal is to evaluate the preliminary clinical outcome of CXL in Keratoconus patients in Bangladesh after 1 year follow up. Method: This retrospective observational type of study was conducted among 40 patients who fulfilled criteria from Bangladesh Eye Hospital, Chittagong January 2014 to January 2019. Results: During the study, most of the patients belong to 31-40 years age group, 48%. Treated eyes showed a flattening of the steepest simulated keratometry value (K-max) by an average of 0.74 diopters (D) (P=.004) at 3 months, 0.92 D (P=.002) at 6 months, and 1.45 D (P=.002) at 12 months. A trend toward improvement in best spectacle-corrected visual acuity was also observed. In the control eyes, mean K-max steepened by 0.60 D (P=.041) after 3 months, by 0.60 D (P=.013) after 6 months, and by 1.28 D (P<.0001) after 12 months. Best spectacle-corrected visual acuity decreased by logMAR 0.003 (P=.883) over 3 months, 0.056 (P=.092) over 6 months, and 0.12 (P=.036) over 12 months. Conclusion: From our study we can conclude that, CXL could be considered as a promising first line treatment for most patients with progressive KCN, especially considering our encouraging long-term results.