DOI: 10.36347/gamj.2024.v05i02.003

Pages: 31-36

Introduction: Immune-Mediated Inflammatory Diseases (IMIDs) are characterized by three nosological entities and their nosological sub-entities: (i) autoimmune diseases (systemic autoimmune diseases, organ-specific autoimmune diseases), (ii) autoinflammatory diseases (monogenic autoinflammatory diseases, polygenic autoinflammatory diseases: "systemic" polygenic autoinflammatory diseases and "organ-specific" polygenic autoinflammatory diseases) and (iii) inflammatory diseases of undetermined mechanism (neoplasms, paraneoplastic syndromes and inflammatory diseases of iatrogenic origin). Here, to our knowledge, we report the first suspected case of interrelated type of diseases within the three nosogical entities of immune-mediated inflammatory diseases (seronegative for elderly onset rheumatoid arthritis (SEORA) as autoimmune disease, giant cell arteritis with polymyalgia rheumatica as autoinflammatory disease and adenomyoma of prostate as inflammatory disease of undetermined mechanism) associated with multifactorial osteoporosis and an acute-onset disease diagnosed in a sexagenarian man. Case Description: A 60-year-old man with no past medical history. At his first presentation in January 2019, he was diagnosed firstly SEORA with lung rheumatoid nodules and suspected subcutaneous rheumatoid nodules, secondly multifactorial osteoporosis related to smoking, alcohol and coffee consumption, denutrition and SEORA and thirdly adenomyoma of prostate. He was discharge with appropriate medication. He discontinued on his own initiative. After 5 months, he was hospitalized with pain and stiffness in the larger joints predominantly in the shoulder joint and hip joint then in the smaller joints. He reported additionally headache predominantly over the right temple, which was accompanied with blurred vision and jaw claudication. Physical findings included tenderness in the shoulder with limited abduction and in the hip; right temporal artery tenderness with weak pulse. ............