DOI: 10.36347/sasjm.2024.v10i05.014

Pages: 361-364

Nosocomial infection is an infection acquired in a healthcare establishment. It is acquired more than 48 hours after admission [1]. Intensive care units are considered a reservoir of multi-resistant bacteria due to the critical condition of patients and the practice of certain invasive care [2]. NI constitute a public health problem marked by high morbidity and mortality. The objectives of our study are:  Detail the epidemiological profile of IN  List ATB-resistant germs  Determine the main prognostic factors We carried out a prospective study from January to June 2022 including patients hospitalized during the period in the HIT RUCH department. Patients whose stay was less than 48 hours were excluded. The diagnosis of IN was suggested based on clinical and paraclinical signs and then confirmed by bacteriological analyses. The resistance profile of the germs to ATB was reported by the results of the antibiogram. Among the 92 patients who stayed more than 48 hours in intensive care, 19 presented with IN, an incidence of 20.65%, of which 89% were male and the median age was 51.7 years. The time to IN acquisition was 5.1 days. IN at the pulmonary site were predominant with a percentage of 36.84%. The germs responsible for IN were dominated by BGN including acinetobacter baumanii with 42.1% and its resistance to ATB was 100% to C3G, 65.6% to amikacin; CGP germs were represented by staphylococcus aureus with 15%. IN-related mortality was 42%. It appears in the light of our results that IN and resistance of germs to ATB are worrying. Judicious use of ATB, hand washing and use of sterile equipment are essential to reduce the incidence of nosocomial infection.