DOI: 10.36347/SASJM.2019.v05i09.005

Pages: 158-161

Primary hepatic lymphoma (PHL) is a rare extranodal non-Hodgkin’s lymphoma which can be missed easily. We present a case of extranodal high grade lymphoma of the liver in a 57-year-old lady with no particular pathological history. Lymphoma manifested with sharp significant pain in the right hypochondrium, weakness, and profuse night sweats. Contrast enhanced computed tomography scan (CT-scan) of the abdomen revealed heterogeneous segment VI tumor process measuring 8 cm long axis. Histological and immunohistochemical features of the tumors allowed diagnosis of diffuse large B-cell lymphoma (DLBCL). To exclude secondary liver lesion by non-Hodgkin lymphoma, chest and small pelvis CT-scan and study of bone marrow were performed. The patient was refractory to R-CHOP, RDAOX and R-GEMOX. She was placed in palliative care and she died three weeks after the cessation of treatment. Primary hepatic lymphoma is extremely rare, and its management is debatable in the absence of international recommendations