DOI: 10.36347/sjmcr.2024.v12i05.040

Pages: 737-739

Our article reports on two cases of pediatric vaginal yolk sac tumors (YSTs), underscoring the diagnostic challenges posed by their similarities to other vaginal tumors, particularly in differentiating from embryonal rhabdomyosarcoma based on clinical and radiological presentations. Emphasizing the critical role of MRI, histological examination, and alpha-fetoprotein levels in diagnosis, we highlight the complexities of treatment, which has evolved from radical surgeries to more conservative approaches with adjuvant chemotherapy, aiming to preserve future sexual and reproductive functions. Our findings advocate for individualized treatment plans and stress the importance of accurate diagnosis and the potential need for alternative therapeutic strategies in cases of atypical response to treatment.