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Scholars Journal of Applied Medical Sciences | Volume-8 | Issue-08
Antimicrobial Susceptibility Pattern of Community Acquired Pneumonia among Adults in Tripura, North-Eastern India
Dr. Mousumi Paul, Dr. Tapan Majumdar, Dr. Pradip Bhowmik
Published: Aug. 28, 2020 | 112 138
DOI: 10.36347/sjams.2020.v08i08.022
Pages: 1901-1907
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Abstract
Community Acquired Pneumonia (CAP) is the most common respiratory tract infection in day to day practice. The knowledge of organism commonly causative of CAP helps in early empirical treatment initiation. The true incidence of pneumonia acquired in the community is unknown, but this is a common clinical problem worldwide especially in developing countries and remains a leading cause of death in India. There are very few and conflicting Indian data regarding the bacteriological etiology of community acquired pneumonia (CAP). Adding to this agony, there is no much credible data from the north-eastern part of India. Hence the following study was undertaken to study the aerobic bacteriological profile and antimicrobial susceptibility pattern of community-acquired pneumonia among adult. A total of 220 patients were studied. Age group varied from 18 years to 85 years. Most common organisms responsible were Klebsiella pneumonia, Staphylococcus aureus, Pseudomonas aeruginosa, Haemophilus influenzae, Streptococcus pneumoniae. Gram negative Organisms were found to be sensitive for Meropenem (100%), followed by Piperacillin-Tazobactum (87.95%), Ami¬kacin (84.34%), Ceftriaxone (73.49%) and Levofloxacin (69.88%). Highest number of resistance was seen against Amoxycillin-Clavulanic acid (74.39%), followed by Ceftazidime (66.67). For gram positive cocci, highest sensitivity was shown to Clindamycin (83.67%), followed by Doxycycline (81.63%) & Ceftriaxone (73.47%), Conclusion: Klebsiella pneumoniae was the most common pathogen incriminated in CAP, followed by Staphylococcus aureus. Most of the organisms were found to be sensitive to carbapenem, third generation cephalosporins, fluroquinolones, macrolides.