DOI: 10.36347/sasjm.2024.v10i05.027

Pages: 420-423

Objective: The purpose of this case report is to describe a case where calcium pyrophosphate dehydrate crystal deposition disease (CPPD) simulated osteoarthritis of the knee. Clinical Features: A 76-year-old woman had a 10 days history of severe right knee pain accompanied by mild swelling and fever, the onset was sudden and did not involve a history of trauma or previous injury to the right knee. Inspection and palpation revealed pain along the medial joint line and marked difficulty ambulating. Diagnostic imaging was performed and showed degenerative changes with diffuse calcification of the fibrocartilage and hyaline articular cartilage within the knee joint and the medial collateral ligament consistent with the appearance of CPPD crystal deposition. Intervention and Outcome: the patient was treated as pseudogout disease and was prescribed colchicine and non¬ steroidal anti-inflammatory drug (NSAID); Eight days later, at follow-up, the knee ‘s pain and immobilization symptomatology reduced 50% and 90% after 4 weeks. Conclusion: Although knee osteoarthritis is much more common than knee CPPD, it is important to consider both diagnoses in elderly patients who present with unilateral knee pain. Diagnosis should be based on clinical presentation, history, and radiographic or histological means to ensure accuracy and proper diagnosis.