DOI: 10.36347/sajp.2024.v13i06.003

Pages: 219-226

Tablet is defined as solid pharmaceutical dosage form containing drug substance generally with suitable diluents and prepared by either compression or molding methods. Tablets remain popular as a dosage form because of the advantages afforded, both to the manufacturer (e.g. simplicity and economy of the preparation, stability, and convenience in packing, shipping and dispensing) and the patient. Because of their composition, method of manufacture or intended use, tablets present a variety of characteristics and consequently there are several categories of tablets. Tablet formulation and design may be described as the process whereby the formulator ensures that the correct amount of the drug in the right form is delivered at or over the proper time at the proper rate and in the desired location, while having its chemical integrity protected to that point. Latest concepts and regulations focus on bioavailability, bioequivalence and validation etc. impact formulation designing and manufacture.