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SAS Journal of Medicine | Volume-1 | Issue-01
Role of Histopathology On Autopsy Study: An Audit
Nada Chettian Kandy, Muktha R Pai, Reba Philipose T
Published: May 30, 2015 | 82 190
DOI: 10.36347/sasjm.2015.v01i01.002
Pages: Page: 7-15
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Abstract
The aim of present study is to determine the age and gender distribution of the deceased individuals and compare histological and necropsy diagnosis of different organs. Fifty-one cases of death that underwent pathological autopsies in the AJIMS hospital were reviewed. The autopsy records, clinical case notes, gross specimens and histopathological slides were retrieved. The results were analyzed according to age, gender and cause of death. The frequencies of discordant versus concordant diagnoses were compared using Mcnemar’s test and Weighted kappa statistics. The age and gender wise distribution of cases showed that the incidence of death was higher in fourth and fifth decades of life (23.52%). Our study showed that in maximum cases pathology was detected in cardiovascular system (78.43%) followed by respiratory system (74.50%). Atherosclerosis with narrowing of coronary arteries observed during autopsy in 47.50% of cases and confirmed by histopathology in 50% of cases. Pneumonic changes observed in lungs (36.84%) cases, confirmed by histopathology in 26.31%. Pulmonary edema was noticed during autopsy in 23.68% cases and tuberculous changes in lungs observed in 10.52% cases, confirmed by histopathology in 15.78% cases in each of both conditions. Post autopsy examination of tissues should be continued if the resources are available because there can be discordance between macroscopic and microscopic diagnosis. Histopathological examination did not affect the legal status in the cases studied. However it facilitated detection of incidental or co- existing disease in the deceased individual in a forensic autopsy.