DOI: 10.36347/SASJM.2019.v05i10.001

Pages: 173-176

This study compared intranasal midazolam versus intravenous midazolam for procedural sedation in pediatric patients. It was a Prospective randomized study. Total 100 children between 1-12 years of age of either sex for various invasive and noninvasive procedures requiring sedation received either intravenous midazolam (0.2mg/kg) or intranasal midazolam (0.2mg/kg) with repeat dosing through same route (0.1mg/kg) if not sedated within 10 minutes. Time to sedation was significantly shorter in IVM group as compared to INM group [2.38 ± 0.96 min. vs 8.56 ± 1.75 min, p value <0.0001]. Duration of post procedure sedation, hypoxemia, respiratory depression, hypotension and vomiting had no statistical significance.