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Scholars Journal of Applied Medical Sciences | Volume-12 | Issue-08
Value of Renal Artery Resistive Index in Nonazotaemic Cirrhotic Patients with Ascites
Prof. Akm Shamsul Kabir, Dr. Miah Wahiduzzaman, Prof. Fakhrul Alam, Professor Chanchal Kumar Ghosh, Professor Abu Hena Mostofa Kamal, Dr. Arifin Islam Lita, Dr. Md. Kudrat-E-Khuda
Published: Aug. 13, 2024 |
185
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DOI: https://doi.org/10.36347/sjams.2024.v12i08.007
Pages: 949-954
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Abstract
Background: Renal dysfunction is a common complication in patients with liver cirrhosis, with hepatorenal syndrome (HRS) being the most severe form. HRS is characterized by disturbances in both circulatory and kidney functions and is diagnosed by excluding other causes of renal failure. Objective: This study aimed to measure the renal artery resistive index (RI) in non-azotaemic cirrhotic patients with ascites to predict early renal haemodynamic dysfunction. Methodology: A prospective study was conducted involving 30 cirrhotic patients with ascites and 15 healthy controls. Renal artery RI was measured using Duplex Doppler ultrasonography. Inclusion criteria for patients included normal renal function, as indicated by serum creatinine ≤ 1.2 mg/dl and creatinine clearance rate ≥ 50 ml/min. Results: The mean renal artery RI was significantly higher in cirrhotic patients with ascites (70% had RI ≥ 0.70) compared to controls (all had RI < 0.70). Significant differences were observed in serum bilirubin, SGPT, SGOT, and prothrombin time between cases and controls (p < 0.05). Conclusion: Renal Doppler ultrasonography is a valuable noninvasive method for detecting early renal haemodynamic dysfunction in cirrhotic patients with ascites. Elevated renal artery RI can serve as an indicator of renal dysfunction, aiding in early diagnosis and management.