DOI: https://doi.org/10.36347/gamj.2024.v05i03.005

Pages: 67-71

Vitamin C (ascorbic acid) is a vitamin that can dissolve in water, important in acting against oxidative stress, and acts as co-mediator for biosynthesis carnitine and collagenous fibers, and the anabolism and catabolism of catecholamine, and in addition to its impact on the gut absorption of iron. Human has no ability of manufacturing ascorbic acid. Green leafy vegetables, potatoes, tomatoes, berries, and citrus fruits are major suppliers for vitamin C. It was found that ascorbic acid plays a major role in relieving stress and many disorders related to it like anxiety and depression. Three major mechanisms have been used to explain the anti-stress impact of vitamin C, they include: antioxidative effects, anti-inflammatory effects, and direct effect on hypothalamus-pituitary-adrenal (HPA). This article tries to answer the questions about the mechanisms by which vitamin C can relieve stress and enhance disorders related to stress.