DOI: 10.36347/sjams.2020.v08i09.023

Pages: 2095-2100

Introduction: Ovarian cancer is an alarming health problem in Bangladesh. The annual morality rate per 1, 00,000 people from ovarian cancer in Bangladesh has raised by 40.3% since 1990, an average of 1.8% per year. Globcan predicts changes in the reported incidence of ovarian cancer from 2912 in year 2012 to 3132 to 2015. Recurrent high- grade ovarian cancer is usually associated with short term survival. Disease stage at diagnosis is a strong prognostic variable for predicting patient outcome in ovarian cancer. Aim of the study: to investigate the histological characteristics and stage of ovarian cancer and to correlate with preoperative level of serum CA -125. Material & Methods: This cross sectional study was carried out at the Department of Obstetrics and Gynaecology in Ashiyan Medical College Hospital, Barua Khilkhet, and Dhaka, Bangladesh during the period from August 2018 to July 2019. A total of 100 patients were selected using purposive sampling technique for this study. Data were collected and documented on a preformed and pretested structured questionnaire. Clinical examination and relevant investigation were done and recorded accordingly. Data were processed and analyzed with the help of computer software SPSS 22. Results: Mean age of the study subjects was 45.7 ± 15.2 years with a range of 13-75 years. Table II shows education status of the study subjects. It was observed that half of the study subjects had education up to primary level, 26% had studied up to secondary level, 19% up to higher secondary level and only 5% were graduate. Mean BMI was 23.3± 3.0 kg/m2, mean age of marriage was 16.1± 2.8years and mean CA-125 level was 547.02± 478.74. Maximum study subjects had stage III (44.0%) followed by stage II (24.0%), stage I (21. 0%) and stage IV (11.0%). Also, most of the study subjects had serous tumors (70.0%) followed by mucinous tumors (11.0%), endometrioid adenocarcinoma (8.0%), clear cell tumors (4.0%), malignant tertoma (5.0%), ...............