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Scholars Journal of Applied Medical Sciences | Volume-8 | Issue-09
Uses of Monotherapy and Combination of Antihypertensive Drugs for Hypertensive Patients with Type-2 Diabetes
Dr. Md. Ahsan Habib, Dr. Md. Aminul Hasan, Dr. Md. Rashadul Kabir, Dr. Md. Monwar Hossain
Published: Sept. 30, 2020 | 111 78
DOI: 10.36347/sjams.2020.v08i09.044
Pages: 2205-2211
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Abstract
Background: Now a day association of diabetes in hypertensive patients is a very common issue. In fact, people with both diabetes and hypertension have approximately twice the risk of cardiovascular disease as nondiabetic people with hypertension. Besides monotherapy combinations of antihypertensive drugs are essential for many cases of hypertensive patients with type-2 diabetes. We have not enough data regarding the uses of monotherapy and combination of antihypertensive drugs for hypertensive patients with type-2 diabetes. Aim of the study: The aim of this study was to assess the uses of monotherapy and combination of antihypertensive drugs for hypertensive patients with type-2 diabetes. Methods: This was an observational cross sectional study and it was conducted in Dhaka Medical College Hospital and BIRDEM Hospital during the period from July2016 to June 2017. In total 140 diagnosed hypertensive patients with type 2diabetes mellitus attending to the Endocrine Departments of Dhaka Medical College Hospital and BIRDEM Hospital completed the full tenure of the study were finalized as the study population. After data analysis, results were find out according to the objectives, study result were presented in the form of tables, charts and description of the key findings according to need. The collected data were also be entered and analyzed using statistical software SPSS version 16. Result: In total 66 (47.1%) patients of this study taken monotherapy and 74 (52.9%) patients taken combination drugs. In this study, 73%, 23% and 4% patients taken double, triple and quadruple combination of antihypertensive drugs respectively. As monotherapy, ARBs, CCBs, ACEIs, Beta Blockers, and diuretics were used in 35%, 23%, 20%, 16% and 6% patients respectively. In DMCH, ARB + Diuretics (8) and ARB +CCB (8) were most commonly used combinations. On the other hand, in BIRDEM, ARB + Diuretics (13) were most commonly used combinations and then B. Blocker + CCB (11) were most commonly...