DOI: 10.36347/sjams.2020.v08i10.009

Pages: 2251-2255

A case-control type of study was conducted over a period of 6 (Six) months following approval in the Department of Paediatrics,  Dhaka Shishu (Children) Hospital, Dhaka, Bangladesh during the period from October 2012 to April 2013. Our aim was to assess laboratory findings of typhoid fever in children in Bangladesh.   The sample size for this study was 240 (120 cases and 120 controls).  Out of 120 participants in each group 79.2% cases and 68.3% controls respondents were mother of the children. In both groups, most of the study participants were  from  younger  age group ≤ 5 years; 63.3% of cases and 80.8% of control. Mean ± SD of age were (5.1042 ± 3.11575) for cases  and  (3.5951 ± 2.50218) for controls Age distribution of the children was statistically significant where p -value was 0.0001 for t-test and 0.01151045 for chi-square (p<0.05). There was no positive association of different blood group but when each group was individually considered, blood group ‘B’ indicated there may be some positive association  (RR = 1.4505, OR = 1.8713 and χ2 = 4.66, p = 0.030873). Only 3.3% children in case group and 4.2% in control group had Rh negative blood group. Widal test result was positive in 83.3% of cases; the remaining 16.7% were found to be Widal negative. The difference was statistically significant (χ2 = 18.22, p =0.0001. Blood culture was done in only 50 (41.7%) participant from the case group; out of them negative culture was obtained in 4 individuals,  the difference was statistically significant (χ2 = 52.585, p = 0. (P < 0.05). Typhoid fever has a strong relation with socio-economic conditions and blood phenotypes.