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Scholars Journal of Applied Medical Sciences | Volume-12 | Issue-09
Acute Pancreatitis Caused by Bortezomib: Report of one Case and Literature Review
Intissar Lasfar, Hanane Aksim, Oualid Hadadia, Rachid Akka
Published: Sept. 25, 2024 | 129 87
DOI: https://doi.org/10.36347/sjams.2024.v12i09.016
Pages: 1211-1215
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Abstract
Drug-induced pancreatitis has been rarely reported. Bortezomib is a selective and reversible proteasome inhibitor used for the treatment of patients with multiple myeloma (MM). We describe the case of a patient with multiple myeloma who developed acute pancreatitis after treatment with bortezomib, commonly used in the treatment of this disease. The patient was admitted to the hospital with symptoms of AP. Common etiological factors of AP were all excluded. The patient was later diagnosed as having bortezomib-induced pancreatitis. We reviewed the available medical literature on this topic and found eleven other similar cases.