DOI: https://doi.org/10.36347/sjams.2024.v12i10.001

Pages: 1257-1261

Introduction: Contrast-Induced Nephropathy (CIN) typically occurs within 24 to 72 hours after contrast media exposure, potentially leading to serious complications. The purpose of the study was to clinically analyze renal function changes following contrast media exposure and explore strategies for prevention and management. Aim of the study: The aim of the study was to clinically analyze renal function alterations following contrast media exposure. Methods: This prospective observational study included 140 patients who underwent imaging procedures with contrast media at the Department of Nephrology, Colonel Maleque Medical College, Manikganj, Bangladesh, from January 1, 2019, to December 31, 2023. Patients aged 18 years and above, with no pre-existing severe renal impairment, were included. Data on serum creatinine, risk factors such as diabetes and hypertension, and renal function outcomes were collected and analyzed using SPSS version 22.0. Result: The majority of patients (42.86%) were aged 57–61 years, with 64.29% being male. Post-contrast serum creatinine were less than 80 µmol/L in 50.00% of patients and 14.29% developed contrast-induced nephropathy (CIN). Diabetes mellitus was significantly more prevalent among CIN patients, occurring in 60.00% compared to 19.16% in non-CIN patients. Among those with CIN, 65% achieved renal function recovery within 7 days. Conclusion: Exposure to contrast media can significantly alter renal function. Incidence of contrast-induced nephropathy was 14.29%. Higher risk in patients with pre-existing conditions and favorable short-term recovery, though some may experience persistent renal dysfunction.