DOI: https://doi.org/10.36347/sjmcr.2024.v12i10.015

Pages: 1678-1682

Neurofibromatosis type 1 (NF1), also known as Von Recklinghausen disease, is a multisystemic neurocutaneous disorder with an autosomal dominant inheritance and variable expressivity. It affects all races with a sex ratio of 1 and a prevalence of 1 in 3,000 to 4,000 births, with 40 to 50% of cases being sporadic. Studies suggest that psychiatric disorders are more common in patients with NF1 than in the general population; the total prevalence of psychiatric pathology, across all diagnoses, is estimated at 33%. Two-thirds of these disorders are considered moderate to severe and vary from one patient to another. In this work, we will present the case of a 10-year-old child who was diagnosed with epilepsy at the age of 5 and with NF1 at the age of 6. The child was referred from the children’s hospital to the child psychiatry department at Arrazi Hospital for management of behavioral problems, suicidal ideation, and academic difficulties. We will also review the literature on the psychiatric manifestations in patients with NF1.